ノバルティスさんのインスタグラム動画 - (ノバルティスInstagram)「Visualizing molecular structures is a fundamental starting point for chemical biology and drug discovery. Throughout its history, Novartis has embraced cutting-edge technologies to accomplish this. Among the more recent is cryo-electron microscopy (#CryoEM), a revolutionary imaging tool that can render high-resolution images of proteins that help researchers better understand these building blocks of life and how they might contribute to disease. With this structural information, scientists at Novartis and beyond can use chemical biology to develop custom-built molecules that fit in the pockets and grooves on the surface of proteins involved in disease – providing biological insights and serving as starting points for new potential medicines. “Cryo-EM is a rising star among structural biology methods because it’s opening doors for so many larger drug targets and protein complexes that cannot be crystallized and so have been out of reach until now.” – Christian Wiesmann, Director, Global Protein Sciences for NIBR’s Chemical Biology and Therapeutics Group. #structuralbiology #chembio」5月25日 18時06分